In addition, one of the key issues that characterize the current state of antibiotic drug discovery ... availability and use of antibacterial and antifungal agents in recent years has resulted ...

Pathogens detected only in the BAL fluid were not susceptible to a standard broad spectrum antibiotic and antifungal regimen including teicoplanin, ceftriaxon, tobramycin, and amphotericin B in 12 of ...