Proton pump inhibitors (PPIs) are a class of very effective and generally safe medicines used to treat heartburn, gastroesophageal reflux disease (GERD), and gastric ulcers.But not everyone who ...

Objective To determine whether proton pump inhibitors (PPIs) are associated with an increased risk of colorectal cancer, compared with histamine-2 receptor antagonists (H2RAs). Design The United ...

Objective To determine whether new users of proton pump inhibitors (PPIs) are at an increased risk of gastric cancer compared with new users of histamine-2 receptor antagonists (H2RAs). Design Using ...

Objectives This study aimed to assess whether the combined use of proton pump inhibitors (PPIs) with non-steroidal anti-inflammatory drugs (NSAIDs) or antibiotics (penicillins, macrolides, ...

Both pharmacokinetic and pharmacodynamic differences can be observed among the different proton pump inhibitors (PPIs), which might influence their clinical application. Pharmacokinetic Properties ...

Proton pump inhibitors (PPIs) are a group of drugs that ... so it’s important to discuss your full medication list with your healthcare provider before starting a PPI.

The development of the proton pump inhibitors (PPIs) seemed to be the answer or partially helpful for the treatment of symptoms. It now appears that this group of drugs is associated with serious ...

Aims Proton pump inhibitors (PPIs) produce negative inotropic effects on the human myocardium at clinically relevant plasma concentrations. We conducted this study to determine whether PPI use was ...

This trial will test a context-specific, patient-centred intervention that draws on health psychology and behaviour change principles to support general practitioners (GPs) and patients in ...

gmail.com Background Clopidogrel as an adjunct to aspirin has improved outcomes after acute coronary syndromes, but laboratory studies suggest a reduced antiplatelet effect when proton pump inhibitors ...