Pentoxifylline is a nonselective phosphodiesterase inhibitor thought to have anti-inflammatory and antifibrogenic activity. It has been used widely to treat other fibrotic disorders, which led the ...

Like pentoxifylline, cilostazol and several of its metabolites exhibit these antiplatelet and vasodilatory actions through the inhibition of phosphodiesterase activity. This inhibition of ...

Cilostazol and pentoxifylline are the only two drugs with FDA-approved labeling for use in treating IC. Both drugs have been shown to increase pain-free walking time and total distance walked ...