The results of most clinical trials with the thistle (Silybum marianum) extract, silymarin, are difficult to interpret because of a variety of reasons: small sample size, variability in type and ...

The flavonoid silymarin and one of its structural components, silibinin, are substances with documented hepatoprotective properties. Their mechanisms of action are still poorly understood.

This study aimed to investigate the hepatoprotective potential of dapagliflozin and silymarin alone and in combination against CCl 4-induced hepatotoxicity in Wistar rats. Methods 30 adult Wistar rats ...

Gaertn., and is standardized according to the content of silymarin. The available toxicological and clinical evidence supports the safe consumption of milk thistle seed extract as a supplemental ...