In rare cases, thigh pain can be a sign of a life-threatening condition, such as cancer. Typically, though, a more likely cause is muscle strain, nerve injury, or osteoarthritis.Your healthcare ...

the spasms occur primarily at night and can awaken the patient from sleep. More severe leg cramps can cause pain that lasts several days after the cramp occurs. While leg cramps tend to resolve on ...

This is especially true with meniscal tears in which two wedge-shaped pieces of cartilage between the thigh and calf ... several possible reasons why knee pain worsens at night.