A US district court has said that a key patent held by Astellas on its Myrbetriq drug for urinary incontinence is invalid, in a setback to its efforts to defend the blockbuster therapy from ...

Importance: The most used overactive bladder (OAB) medications are anticholinergics, which professional societies recommend avoiding in older patients given dementia risk. Cost prevents patients from ...

adrenoceptor agonist (mirabegron) is a recently introduced class of drug which acts on the β3 receptors present in the bladder promoting detrusor relaxing and improving the bladder storage ...

It is still facing challenges on the patent front – notably to pharmacologic stress agent Lexiscan (regadenoson injection), overactive bladder therapy Myrbetriq (mirabegron) and the looming loss ...

While medication can provide symptom relief, it does not necessarily address underlying maladaptive behaviors, and is therefore considered by many clinicians and adjunct to treatment, rather than ...

These drugs are available in oral and transdermal preparations and may be given multiple times daily or as extended-release medications. All of the medications in this class may have side effects ...

They explore the drugs’ specificity, pharmacokinetics and toxicity profile and show that they are efficacious in the context of colorectal cancer.

Reaching the depths of the respiratory tract is hard even with vapor-based drug delivery. Here, the authors devise inhalable biohybrid microrobots that, thanks to their motility, reach deeper ...

Cinacalcet for the treatment of secondary hyperparathyroidism in patients with end-stage renal disease on maintenance dialysis therapy TA117 24 January 2007 24 January 2007 Methadone and buprenorphine ...

Guidance on the use of capecitabine and tegafur with uracil for metastatic colorectal cancer TA61 27 May 2003 27 May 2003 Guidance on the use of drugs for early thrombolysis in the treatment of acute ...

The thyroid medication levothyroxine should be taken on an empty stomach at around the same time every day. You should avoid eating or drinking for 30 minutes to one hour after taking it. There are ...