For most men, sildenafil is a safe and effective treatment for ED when used as prescribed. However, like all drugs, it comes with its own set of potential side effects and interactions.

In order to address this gap in the literature, a team of Indian researchers has performed a double-blind, randomized, controlled, crossover trial of the safety and efficacy of sildenafil in this ...

Objective: In view of the recent U.S. Food and Drug Administration's warning against the use of sildenafil in pediatric patients, we aimed to provide an updated overview of the dosing and safety ...

longer-term randomized trials will be necessary to define the safety, tolerability, and efficacy of sildenafil for the management of heart failure across the spectrum of ejection fraction.

Methods: This randomised, double blind (DB), placebo controlled, flexible dose study with an open label extension (OLE) assessed efficacy, QoL, and safety of sildenafil citrate in men with MS and ED.

Objective To assess the effect of sildenafil, a phosphodiesterase type 5 inhibitor, on digital ulcer (DU) healing in systemic sclerosis (SSc). Methods Randomised, placebo-controlled study in patients ...

3 patients experienced adverse effects (deterioration of oxygenation and hypotension). Conclusions Sildenafil appears to be well tolerated and safe in most patients with an improvement in 6MWD ...