Age influences blood pressure in both men and women, but the patterns and mechanisms of these changes often differ due to biological and hormonal variations. In general, blood pressure tends to increase with age for both genders, but men typically experience significantly higher levels in middle age compared to women, mainly due to lifestyle factors and physiological differences. Before menopause, women usually have lower blood pressure than men, likely due to the protective effects of estrogen, which can enhance vascular function and maintain arterial flexibility. However, following menopause, women's blood pressure often rises, and by older age, it can surpass that of men, potentially linked to the loss of estrogen and the onset of other age-related health issues. Additionally, older women are more likely to develop conditions such as hypertension due to the accumulation of risk factors over time, including obesity and changes in vascular health. Consequently, while both sexes face an increased risk of hypertension as they age, the trajectory and timing of these changes can differ, underscoring the need for gender-specific health strategies in managing blood pressure in older adults.