Rutin supplements are possibly safe when taken in doses up to 600 mg daily for up to 12 weeks. Rutin is usually well tolerated. Side effects might include headache or stomach upset.

Rutin is generally considered safe when consumed in the amounts found in foods like citrus, onions, and apples. However, rutin supplements may cause specific side effects, including: Dizziness Headache Skin rash Dry mouth Tiredness Nausea

The US Food and Drug Administration has established that rutin supplements are generally safe to use (x). In a small number of people, it may produce side effects such as light-headedness, nervousness, flushing, minor stomach upset, blurred vision, headache, rash, muscle stiffness and fluid accumulation in the knees (x).

Rutin is POSSIBLY SAFE when taken by mouth appropriately in medicinal amounts for a short period of time. It can cause some side effects including headache, flushing, rashes, or stomach upset.