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  2. Verywell Health
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    Cialis vs. Viagra: Differences You Need to Know

    • Both medications, available as generics, are phosphodiesterasetype 5 (PDE5) inhibitors that work by increasing blood flow to the penis. But, the main difference between Cialis and Viagra is how long … See more

    What Is Cialis?

    Cialis (tadalafil) is a type of PDE5 inhibitor that the Food and Drug Administration (FDA) approved in 2003. Like other PDE5 inhibitors, it increases blood flow to the penis. Ther… See more

    Verywell Health
    What Is Viagra?

    Viagra (sildenafil) was the first erectile dysfunction pill approved by the FDA in 1998. Like Cialis, it’s a PDE5 inhibitor that increases blood flow to the penis. The difference i… See more

    Verywell Health
    How Ed Drugs Work

    PDE5 inhibitors work by blocking the breakdown of a substance known as cyclic guanosine monophosphate (cGMP). As a result, there is more nitric oxidein the body. Nitric oxide i… See more

    Verywell Health
    Cialis, Viagra & Levitra ED Medications: Comparison of Erectile ... - WebMD
    WebMD
    How effective is Cialis vs Viagra?
    Cialis and Viagra are equally effective. All PDE5 inhibitors are about 70% effective at helping people have better erections. That means seven out of 10 people who take these drugs as prescribed will have more frequent or longer-lasting erections. However, eating food, particularly high-fat food, can reduce the effectiveness of Viagra.
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